Basic research
Mechanisms, neuroprotection & repair
Investigating how the brain responds to injury and how that response can be modified, from molecular and cellular mechanisms to experimental strategies for neural repair.

Chief Physician · Researcher · Doctoral Supervisor
Clinical practice in traumatic brain injury and neurocritical care. Research in neuroprotection, neural repair and multicentre clinical trials.
Director of Neurosurgery and the Brain Injury Center at Renji Hospital. Clinical work covers traumatic brain injury, cerebral haemorrhage, neurocritical illness, disorders of consciousness and complications after brain injury.
Mechanisms, neuroprotection & repair
Investigating how the brain responds to injury and how that response can be modified, from molecular and cellular mechanisms to experimental strategies for neural repair.
Surgical decisions, critical care & outcomes
Addressing decisions in neurotrauma care through multicentre trials and clinical cohorts, from acute surgery and intensive care to prognostic assessment.
Multicentre randomised controlled trial · 28 hospitals
Decompressive craniectomy did not improve six-month functional outcomes and was associated with more delayed intracranial haemorrhage in the population studied.
Publication detailsPreclinical study · cell and mouse models
The study explored targeted delivery and neural repair in experimental models, providing a preclinical direction for further translational research.
Publication detailsMulticentre randomised controlled trial
The overall comparison did not establish a neurological outcome benefit. Subgroup findings require interpretation as exploratory evidence.
Publication detailsDoctoral supervision connecting neurotrauma practice, basic science and clinical research.
Research directions & enquiriesCo-author of 大脑环游记:漫画神经科学的奇妙世界, an illustrated neuroscience book published by Tsinghua University Press.
Books & community education